HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → Benzoic acid, 3-[(1E)-2-(dimethylamino)ethenyl]-2-nitro-, methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Reactant | Benzoic acid, 3-methyl-2-nitro-, methyl ester | HCID 79621 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Benzoic acid, 3-[(1E)-2-(dimethylamino)ethenyl]-2-nitro-, methyl ester | HCID 771483 | — |
Reaction Steps
A solution of methyl 3-methyl-2-nitrobenzoate (43 g, 0.22 mole), dimethylformamide dimethyl acetal (52.5 g, 0.44 mole) and piperidine (18.7 g, 0.22 mole) in dimethylformamide (120 ml) was heated under reflux for 24 hours, cooled and poured into water to give the crude product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05281593 |
| Source dataset | uspto-grants-1994_01 |
| ORD ID | ord-28349c0abea0423eb5800fe16b44b1b2 |
| Source note | uspto-grants-1994_01 |