HCID 14519867, compound → HCID 14519890, compound

HRID 1198620Notes

Reaction equation

HRID 1198620 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=O)=[C:4]([O:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[CH3:18])[CH:3]=1>CO>[Cl:1][C:2]1[CH:3]=[C:4]2[C:5](=[CH:9][CH:10]=1)[C:6](=[O:8])[C:17]1[CH:16]=[CH:15][CH:14]=[C:13]([CH3:18])[C:12]=1[O:11]2

Participants

3

Reactant 1

HCID 14519867HCID 14519867, compound

Product 1

HCID 14519890HCID 14519890, compoundYield 90%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The above crude acid (IV: R1 =4-Cl, R3 =H) was cyclized with polyphosphate ester as in Example A to give a 90% yield of 6-chloro-4-methylxanthenone (VI: R1 =6-Cl, Z=CH3), mp (MeOH) 145°-146° C. Anal. (C14H9ClO2) C,H,N.

Sources & evidence

ORD record
ord-49a2556f328c4565a012ee1aa9a2cecf
Source dataset
uspto-grants-1994_01
Patent number
US05281620

Reaction notes

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