Acetic Anhydride → HCID 54319486, compound

Participants

Reaction Steps

To a solution of the ketone from Step 1 (1.91 g) in CH2Cl2 (20 mL) was added Ac2O (1.5 mL), Et3N (2.3 mL) and DMAP (40 mg). The reaction mixture was stirred at r.t. for 18 hr then diluted with Et2O and a saturated solution of NH4Cl. The organic phase was extracted, washed with H2O, brine, dried over MgSO4, and the solvent evaporated to afford the title product as a foam which was used as such in the next step.

Provenance & Evidence