6-(4-Bromophenyl)-3-pyridineacetaldehyde → HCID 19867235, compound

HRID 1198844Notes

Reaction equation

HRID 1198844 reaction equation
BrC1C=CC(C2C=CC(CC=O)=CN=2)=CC=1.[Br:17][C:18]1[CH:23]=[CH:22][C:21]([C:24]2[CH:29]=[CH:28][C:27]([CH2:30][CH:31]=[CH:32][O:33]C)=[CH:26][N:25]=2)=[CH:20][CH:19]=1>>[Br:17][C:18]1[CH:19]=[CH:20][C:21]([C:24]2[CH:29]=[CH:28][C:27]([CH2:30][CH2:31][CH:32]=[O:33])=[CH:26][N:25]=2)=[CH:22][CH:23]=1

Participants

3

Reactant 2

HCID 540726296-(4-Bromophenyl)-3-pyridineacetaldehydeHCID 54225454HCID 54225454, compound

Product 1

HCID 19867235HCID 19867235, compound

Procedure

[2-(p-Bromophenyl)-5-pyridyl]acetaldehyde is converted in an analogous manner to paragraph (a) into 2-(p-bromophenyl)-5-(3-methoxy-2-propenyl)pyridine and this is then hydrolyzed in an analogous manner to paragraph (b) to give 3-[2-(p-bromophenyl)-5-pyridyl]propionaldehyde.

Sources & evidence

ORD record
ord-06d50cdaddfb42e39859b709f2d2d14c
Source dataset
uspto-grants-1990_02
Patent number
US04898455

Reaction notes

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