HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → 2-methoxy-6[(N-2-nitrophenyl)-amino]-8-methylquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 1-Fluoro-2-nitrobenzene | HCID 73895 | — |
| Reactant | 6-Amino-2-methoxy-8-methylquinoline | HCID 19867071 | — |
| Product | 2-methoxy-6[(N-2-nitrophenyl)-amino]-8-methylquinoline | HCID 19867716 | — |
Reaction Steps
This compound, m.p. 185°, was prepared similarly to Preparation 20 using 2-methoxy-6-amino-8-methylquinoline, 1-fluoro-2-nitrobenzene, and sodium carbonate as starting materials. The product was characterised spectroscopically and used directly in Preparation 17 without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04898872 |
| Source dataset | uspto-grants-1990_02 |
| ORD ID | ord-39a85318e462431ca299a15576a8cc13 |
| Source note | uspto-grants-1990_02 |