Sulfuric Acid → HCID 14371402, compound

Participants

Reaction Steps

A solution of 6.2 g of S-[4,6-dichloro-2-[bis(4-fluorophenyl)methyl]phenyl] N,N-dimethylthiocarbamate from stage (c) in ether was added dropwise, while cooling in ice, to a suspension of 0.8 g of lithium aluminum hydride in absolute ether. The mixture was stirred at room temperature for 90 min and was hydrolyzed, while cooling in ice, with 2 N sulfuric acid (pH 3). It was extracted several times with ether, the solution was dried over magnesium sulfate, and the solvent was removed in vacuo. The thiophenol remained as residue (5.3 g of viscous oil, 100% yield) and was pure by TLC (100% toluene, Rf =0.66); melting point 95° C.

Provenance & Evidence