Dimethylamine → HCID 19867806, compound

HRID 1199025Notes

Reaction equation

HRID 1199025 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH2:17][C:18]([OH:20])=O)[C:5]2[C:6]([CH:16]=1)=[C:7]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[O:8][N:9]=2.[CH3:21][NH:22][CH3:23]>>[Cl:1][C:2]1[CH:3]=[C:4]([CH2:17][C:18]([N:22]([CH3:23])[CH3:21])=[O:20])[C:5]2[C:6]([CH:16]=1)=[C:7]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[O:8][N:9]=2

Participants

3

Reactant 2

HCID 674DimethylamineHCID 14835398HCID 14835398, compound

Product 1

HCID 19867806HCID 19867806, compound

Procedure

The title compound is prepared by reacting the acid chloride of 5-chloro-3-phenyl-2,1-benzisoxazole-7-acetic acid and dimethylamine in an aprotic solvent. The solution is washed with hydrochloric acid and evaporated. The title compound is obtained from the residue by conventional crystallization from alkanolic solution or by chromatography.

Workup

  1. customThe title compound is prepared
  2. washThe solution is washed with hydrochloric acid
  3. customevaporated

Sources & evidence

ORD record
ord-43b75b2ecf4f4060abc70f1811698846
Source dataset
uspto-grants-1990_02
Patent number
US04898874

Reaction notes

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