1-Acetylpiperazine → HCID 19867789, compound

HRID 1199032Notes

Reaction equation

HRID 1199032 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH2:17][C:18]([OH:20])=O)[C:5]2[C:6]([CH:16]=1)=[C:7]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[O:8][N:9]=2.[C:21]([N:24]1[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]1)(=[O:23])[CH3:22]>>[C:21]([N:24]1[CH2:29][CH2:28][N:27]([C:18](=[O:20])[CH2:17][C:4]2[C:5]3[C:6](=[C:7]([C:10]4[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=4)[O:8][N:9]=3)[CH:16]=[C:2]([Cl:1])[CH:3]=2)[CH2:26][CH2:25]1)(=[O:23])[CH3:22]

Participants

3

Reactant 2

HCID 837951-AcetylpiperazineHCID 14835398HCID 14835398, compound

Product 1

HCID 19867789HCID 19867789, compound

Procedure

The title compound is prepared by reacting the acid chloride of 5-chloro-3-phenyl-2,1-benzisoxazole-7-acetic acid with N-acetylpiperazine in an aprotic solvent and washing the reaction mixture with sodium bicarbonate solution.

Workup

  1. washwashing the reaction mixture with sodium bicarbonate solution

Sources & evidence

ORD record
ord-23461252bdce4735990923f6c0d5ef9e
Source dataset
uspto-grants-1990_02
Patent number
US04898874

Reaction notes

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