HuagongsheHuagongshe Chemistry Print Report · For research reference only
Butylamine → HCID 19867649, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Butylamine | HCID 8007 | — |
| Reactant | HCID 19867644 | HCID 19867644 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 19867649 | HCID 19867649 | 56% |
Reaction Steps
The procedure is as in Example 44, but starting with [2-(7-methoxy-1,8-naphthyridin-2-yl)-3-oxo-1-isoindolinyloxy]acetic acid (4.5 g) in anhydrous dimethylformamide (100 cc), N,N'-carbonyldiimidazole (2 g) and butylamine (0.73 g). After recrystallization in acetonitrile, [2-(7-methoxy-1,8-naphthyridin-2-yl)-3-oxo-1-isoindolinyloxy]-N-butylacetamide (2.35 g), m.p. 170° C., is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04898871 |
| Source dataset | uspto-grants-1990_02 |
| ORD ID | ord-4d6bc00fc4564482a1dcae5e0eb08bba |
| Source note | uspto-grants-1990_02 |