HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxyethylamine → HCID 70374171, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxyethylamine | HCID 8018 | — |
| Reactant | HCID 19867644 | HCID 19867644 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 70374171 | HCID 70374171 | 82.1% |
Reaction Steps
The procedure is as in Example 44, but starting with [2-(7-methoxy-1,8-naphthyridin-2-yl)-3-oxo-1-isoindolinyloxy]acetic acid (3.5 g) in anhydrous dimethylformamide (80 cc), N,N'-carbonyldiimidazole (1.6 g) and 2-methoxyethylamine (0.65 g). After recrystallization in ethanol, [2-(7-methoxy-1,8-naphthyridin-2-yl)-3-oxo-1isoindolinyloxy]-N-(2-methoxyethyl)acetamide (3 g), m.p. 172° C., is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04898871 |
| Source dataset | uspto-grants-1990_02 |
| ORD ID | ord-8b0dc9963f7248d4838ab4e30c8895cd |
| Source note | uspto-grants-1990_02 |