HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methylpropylamine → HCID 19867683, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methylpropylamine | HCID 12315 | — |
| Reactant | HCID 19867644 | HCID 19867644 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 19867683 | HCID 19867683 | 78.3% |
Reaction Steps
The procedure is as in Example 44, but starting with [2-(7-methoxy-1,8-naphthyridin-2-yl)-3-oxo-1-isoindolinyloxy]acetic acid (3.1 g) in anhydrous dimethylformamide (70 cc), N,'-carbonyldiimidazole (1.4 g) and N-methylpropylamine (0.6 g). After recrystallization in ethanol, [2-(7-methoxy-1,8-naphthyridin-2yl)-3-oxo1 -isoindolinyloxy]-N-methyl-N-propylacetamide (2.7 g), m.p. 160° C., is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04898871 |
| Source dataset | uspto-grants-1990_02 |
| ORD ID | ord-0a0d259cd4aa4834b41233761e02ae75 |
| Source note | uspto-grants-1990_02 |