HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isoamylamine → HCID 70374156, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isoamylamine | HCID 7894 | — |
| Reactant | HCID 19867644 | HCID 19867644 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 70374156 | HCID 70374156 | 80.6% |
Reaction Steps
The procedure is as in Example 44, but starting with [2-(7-methoxy-1,8-naphthyridin-2-yl)-3-oxo-1-isoindolinyloxy]acetic acid (3 g) in anhydrous dimethylformamide (65 cc), N,'-carbonyldiimidazole (1.3 g) and 3-methylbutylamine (0.61 g). After recrystallization in ethanol, [2-(7-methoxy-1,8-naphthyridin-2-yl)-3-oxo-1isoindolinyloxy]-N-(3-methylbutyl)acetamide (2.45 g), m.p. 136° C., is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04898871 |
| Source dataset | uspto-grants-1990_02 |
| ORD ID | ord-d9d5622b46564919b706bcbf313b4695 |
| Source note | uspto-grants-1990_02 |