HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1199072Generated: October 31, 2026
1-Pyrrolidinepropanamine → 4,5-Diphenyl-N-[3-(1-pyrrolidinyl)propyl]-1H-pyrazole-1-acetamide
https://huagongshe.com/reaction/1199072
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Pyrrolidinepropanamine | HCID 31670 | — |
| Reactant | 4,5-Diphenyl-1-(ethoxycarbonylmethyl)-pyrazole | HCID 14699551 | — |
| Product | 4,5-Diphenyl-N-[3-(1-pyrrolidinyl)propyl]-1H-pyrazole-1-acetamide | HCID 14699580 | — |
Reaction Steps
A mixture of 15 g (0.049 mol) of ethyl 4,5-diphenyl-1H-pyrazole-1-acetate and 60 mL of N-(3-aminopropyl) pyrrolidine was stirred at 100° C. for 48 hr. The excess aminopropylpyrrolidine was stripped in vacuo and the residue was triturated in ether to yield 5.5 g of product mp 75°-79° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04898880 |
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| Source dataset | uspto-grants-1990_02 |
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| ORD ID | ord-ad9b58a0eccd43158bcf200e2842c882 |
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| Source note | uspto-grants-1990_02 |
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