HCID 67827641, compound → HCID 67827745, compound

Participants

Reaction Steps

A solution of ethyl benzyloxycarbonylphenylalanylphenylalanyl-1-amino-1-cyclopentanecarboxylate (590 mg, 1 mmole) in methanol was hydrogenated by the procedure of Example 1. The methanolic solution was evaporated, dissolved in tetrahydrofurane, evaporated and acylated with glutaric anhydride (175 mg) in dimethylformamide for 2 hours at 80° C. The reaction mixture was evaporated and the product was precipitated with water to give the title compound, m.p. 193° to 196° C. (dimethylformamide-water).

Provenance & Evidence