Sodium Hydroxide → 1,1-Bis(4-pyrrolidinophenyl)ethylene

HRID 1199116Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1199116
[OH-].[Na+].[N:3]1([C:8]2[CH:13]=[CH:12][C:11]([C:14]([C:19]3[CH:24]=[CH:23][C:22]([N:25]4[CH2:29][CH2:28][CH2:27][CH2:26]4)=[CH:21][CH:20]=3)(C)[C:15](O)=O)=[CH:10][CH:9]=2)[CH2:7][CH2:6][CH2:5][CH2:4]1.S(OOS([O-])(=O)=O)([O-])(=O)=O.[K+].[K+]>>[N:3]1([C:8]2[CH:9]=[CH:10][C:11]([C:14]([C:19]3[CH:24]=[CH:23][C:22]([N:25]4[CH2:26][CH2:27][CH2:28][CH2:29]4)=[CH:21][CH:20]=3)=[CH2:15])=[CH:12][CH:13]=2)[CH2:4][CH2:5][CH2:6][CH2:7]1

Komponenten

4

Edukt 3

HCID 14798Sodium HydroxideHCID 24412Potassium PersulfateHCID 142278762,2-Bis(4-pyrrolidinophenyl)propionic acid

Produkt 1

HCID 32960211,1-Bis(4-pyrrolidinophenyl)ethyleneAusbeute 80,1 %

Versuchsvorschrift

Into 100 ml of 5% aqueous solution of sodium hydroxide was dissolved 10 g of 2,2-bis(4-pyrrolidinophenyl)propionic acid. Thereto was added 9.2 g of potassium persulfate and the mixture was reacted with stirring for one hour. The resulting precipitates were collected by filtration and recrystallized from methanol to obtain 7.0 g (yield 80%) of 1,1-bis(4-pyrrolidinophenyl)ethylene, having a melting point of 221°~223° C.

Aufarbeitung

  1. customthe mixture was reacted
  2. customThe resulting precipitates
  3. filtrationwere collected by filtration
  4. customrecrystallized from methanol

Quellen und Nachweise

ORD-Eintrag
ord-165e42f6a8ea47228c4b8cb065e72432
Quelldatensatz
uspto-grants-1990_02
Patentnummer
US04898941

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