Isopropylamine → HCID 19868194, compound

Participants

Reaction Steps

All reactions were carried out in an atmosphere of dry nitrogen using standard Schlenk-techniques (Manipulations of air-sensitive compounds, D. F. Shriver, editor Mc. Graw Hill, N.Y., 1969). Solvents were distilled from sodium prior to use. N-t-butyliminoethylglyoxylate and N-i-propyliminomethylglyoxylate were prepared in a condensation reaction; cf. t-butylamine and i-propylamine with ethylglyoxylate and methylglyoxylate respectively. 2,2,5,5-tetramethyl-1-aza-2,5-disilylacyclopentane-1-acetic acid ethyl ester has been described in Tetrahedron Lett., 22, 1787 (1981). Solutions of n-butyllithium in n-hexane and diethylzinc in n-hexane are commercially available.

Provenance & Evidence