HCID 14478559, compound → HCID 14478554, compound

HRID 1199188Notes

Reaction equation

HRID 1199188 reaction equation
C[C@H](C1C=CC=CC=1)N.[C:10]([O:13][C:14]1[C:19]([CH3:20])=[C:18]([CH3:21])[C:17]([O:22][C:23](=[O:25])[CH3:24])=[C:16]([CH3:26])[C:15]=1[CH2:27][CH2:28][C@@:29]([O:33][C:34]([C:36]1[C:37]([C:42]([OH:44])=[O:43])=[CH:38][CH:39]=[CH:40][CH:41]=1)=[O:35])([C:31]#[CH:32])[CH3:30])(=[O:12])[CH3:11]>C(O)C>[C:10]([O:13][C:14]1[C:19]([CH3:20])=[C:18]([CH3:21])[C:17]([O:22][C:23](=[O:25])[CH3:24])=[C:16]([CH3:26])[C:15]=1[CH2:27][CH2:28][C@@:29]([O:33][C:34]([C:36]1[C:37]([C:42]([OH:44])=[O:43])=[CH:38][CH:39]=[CH:40][CH:41]=1)=[O:35])([C:31]#[CH:32])[CH3:30])(=[O:12])[CH3:11]

Participants

3

Reactant 1

HCID 14478559HCID 14478559, compound

Product 1

HCID 14478554HCID 14478554, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The title compound was prepared from (R)-1,2-Benzenedicarboxylic acid [3-[2,5-bis (acetyloxy)-3,4,6-trimethylphenyl]-1-ethynyl-1-methylpropyl]ester (R)-α-methyl benzenemethanamine (1:1) (salt) by the procedure described in Example 9. The product was a white foam: [α]D25 -15.98° (ethanol).

Sources & evidence

ORD record
ord-6988523674db44f7a9cdd19f2083f8ca
Source dataset
uspto-grants-1990_02
Patent number
US04898953

Reaction notes

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