Ammonia → HCID 178511992, compound

HRID 1199239Notes

Reaction equation

HRID 1199239 reaction equation
O=O.[C:3]1([NH:9][C:10](=S)[NH:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[NH3:19].O>CC([O-])=O.CC([O-])=O.[Cu+2].CO>[C:3]1([NH:9][C:10]([NH:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[NH:19])[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

Participants

7

Reactant 4

HCID 222AmmoniaHCID 962WaterHCID 977OxygenHCID 700999Diphenylthiourea

Product 1

HCID 178511992HCID 178511992, compoundYield 94.2%

Reagents, catalysts & solvents 2

HCID 8895Cupric acetateCatalystHCID 887MethanolSolvent

Procedure

Air is used as the oxygen-containing gas in the following example. 0.1 mol of diphenylthiourea, 1.2 mol of ammonia, and 0.02 mmol of Cu(OAc)2 are reacted with air (pressure of 5 bar) in a solvent mixture of 40 g of water and 40 g of methanol. Diphenylguanidine is obtained in a 94.2% yield at a reaction temperature of 50° C. and a reaction time of 70 min.

Workup

  1. additioncontaining gas in the following example

Sources & evidence

ORD record
ord-a5f1fa7fa50d49988c32bc6b3d20dd3c
Source dataset
uspto-grants-1990_02
Patent number
US04898978

Reaction notes

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