2,4'-Difluorobenzophenone → 1-Fluoro-2-[1-(4-fluorophenyl)ethenyl]benzene

HRID 1199256Notes

Reaction equation

HRID 1199256 reaction equation
Cl[C:2]1C=CC=CC=1C(C1C=CC(F)=CC=1)=O.[F:17][C:18]1[CH:32]=[CH:31][CH:30]=[CH:29][C:19]=1[C:20]([C:22]1[CH:27]=[CH:26][C:25]([F:28])=[CH:24][CH:23]=1)=O>>[F:17][C:18]1[CH:32]=[CH:31][CH:30]=[CH:29][C:19]=1[C:20]([C:22]1[CH:27]=[CH:26][C:25]([F:28])=[CH:24][CH:23]=1)=[CH2:2]

Participants

3

Reactant 2

HCID 676512,4'-DifluorobenzophenoneHCID 74547Methanone, (2-chlorophenyl)(4-fluorophenyl)-

Product 1

HCID 132357851-Fluoro-2-[1-(4-fluorophenyl)ethenyl]benzeneYield 85%

Procedure

The procedure described in Example 1 is repeated except that the 130 parts of 2-chloro-4'-fluorobenzophenone are replaced by 168 parts of 2,4'-difluorobenzophenone, which was converted into the title compound in 85% yield. Distillation, under vacuum, gives a colourless liquid which is pure 1-(2-fluorophenyl)-1-(4-fluorophenyl)ethene (b.pt. 82°/0.2 mm Hg).

Sources & evidence

ORD record
ord-271d830e2b8147e4bbd9ca317551027c
Source dataset
uspto-grants-1990_02
Patent number
US04898997

Reaction notes

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