反应详情

According to the method disclosed in Journal of the American Chemical Society, vol. 76, pages 3352 and 3353 (1954), 150 g of 2-methoxytropone and 84 g of thiourea were added to 255 g of a solution of 28% sodium methoxide in methanol, and stirred at room temperature for 30 minutes. Further, 600 ml of methanol was added thereto and acetic acid was added until the pH of the solution becomes around 5. Deposited crystals were filtered and washed with methanol. The obtained crystals were added to 1 l of methanol, and refluxed with heating for 30 minutes. After being allowed to cool to room temperature, the crystals were filtered and dried.

1. filtrationDeposited crystals were filtered
2. washwashed with methanol
3. additionThe obtained crystals were added to 1 l of methanol
4. temperaturerefluxed
5. temperaturewith heating for 30 minutes
6. temperatureto cool to room temperature
7. filtrationthe crystals were filtered
8. customdried