Methanol → HCID 178423442, compound

HRID 1199346Notes

Reaction equation

HRID 1199346 reaction equation
CO[C:3]1[C:4](=O)[CH:5]=[CH:6][C:7]([CH3:10])=[CH:8][CH:9]=1.[NH2:12][C:13]([NH2:15])=[S:14].CO.C[O-].[Na+].CO>C(O)(=O)C>[SH:14][C:13]1[N:12]=[C:4]2[CH:5]=[CH:6][C:7]([CH3:10])=[CH:8][CH:9]=[C:3]2[N:15]=1

Participants

6

Reactant 4

HCID 887MethanolHCID 2723790ThioureaHCID 14356253HCID 14356253, compoundHCID 23694274Sodium methanolate methanol

Product 1

HCID 178423442HCID 178423442, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

2-Methoxy-5-methyl-2,4,6-cycloheptatrien-1-one (165 g) and 84 g of thiourea were added to 255 g of a 28% sodium methoxide methanol solution, and stirred at room temperature for 30 minutes. Then, 600 ml of methanol was added and acetic acid was added until the pH of the solution becomes around 5. Deposited crystals were collected by filtration, throughly washed with methanol and dried.

Workup

  1. filtrationDeposited crystals were collected by filtration
  2. washthroughly washed with methanol
  3. customdried

Sources & evidence

ORD record
ord-058b92c696aa493db997868389a4ac88
Source dataset
uspto-grants-1990_02
Patent number
US04900648

Reaction notes

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