2-Naphthoyl chloride → HCID 10083909, compound

HRID 1199372Notes

Reaction equation

HRID 1199372 reaction equation
[CH3:1][NH:2][C:3](=[S:6])[NH:4][NH2:5].[CH:7]1[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[CH:10]=[CH:9][C:8]=1[C:17](Cl)=[O:18]>N1C=CC=CC=1>[CH3:1][NH:2][C:3](=[S:6])[NH:4][NH:5][C:17]([C:8]1[CH:9]=[CH:10][C:11]2[C:16](=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:7]=1)=[O:18]

Participants

4

Reactant 2

HCID 752462-Naphthoyl chlorideHCID 2723853N-Methylhydrazinecarbothioamide

Product 1

HCID 10083909HCID 10083909, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

To a stirred room temperature solution of 4-methylthiosemicarbazide (5.91 g, 5.62×10-2 mole) and pyridine (150 ml) was added 2-naphthoyl chloride (10.7 g, 5.61×10-2 mole). After stirring overnight, the pyridine was evaporated at reduced pressure. The concentrate was treated with water and the undissolved product was collected by filtration and dried by suction.

Workup

  1. customthe pyridine was evaporated at reduced pressure
  2. additionThe concentrate was treated with water
  3. filtrationthe undissolved product was collected by filtration
  4. customdried by suction

Sources & evidence

ORD record
ord-c9281fd746634014bc2368dea7eb7761
Source dataset
uspto-grants-1990_02
Patent number
US04900743

Reaction notes

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