HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloroethyl isocyanate → HCID 14627707, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloroethyl isocyanate | HCID 16035 | — |
| Reactant | (+)-7,8-dihydro-6,6-dimethyl-7-hydroxy-8-amino-6H-pyrano[2,3-f]benz-2,1,3-oxadiazole | HCID 11107308 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 14627707 | HCID 14627707 | 83% |
Reaction Steps
To a mixture of 400 mg (1.70 m mol) of 7,8-dihydro-6,6-dimethyl-7-hydroxy-8-amino-6H-pyrano [2,3-f] benzo-2,1,3-oxadiazole and 40 ml of dichloromethane were added 200 μl (1.87 m mol) of 2-chloroethyl isocyanate with stirring at the room temperature, followed by stirring for 6 hours. The precipitated crystals were separated by filter to obtain 480 mg (yield: 83%) of the intended compound as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04900752 |
| Source dataset | uspto-grants-1990_02 |
| ORD ID | ord-ee3afdfcca7a4a1d87393cd593611c28 |
| Source note | uspto-grants-1990_02 |