Triethylamine → HCID 14673941, compound

Participants

Reaction Steps

To a mixture of 180 mg (0.765 m mol) of 7,8-dihydro-6,6-dimethyl-7-hydroxy-8-amino-6H-pyrano [2,3-f] benzo-2,1,3-oxadiazole, 117 μl (0.842 m mol) of triethylamine and 20 ml of methylene chloride were added 73 μl (0.842 m mol) of bromoacetyl chloride with stirring at the room temperature, followed by further stirring for 1 hour. After the completion of the reaction, the precipitated crystal was filtered to obtain 199 mg of the intended compound. (yield: 73%).

Provenance & Evidence