m-Chloroperbenzoic acid → HCID 19866665, compound

Participants

Reaction Steps

The product of step (b) above (1.5 g) was dissolved in ethyl acetate (120 ml) and cooled to -10°. A solution of m-chloroperbenzoic acid (980 mg of 85%) in ethyl acetate (30 ml) was added in one portion and the mixture stirred for 1 hr. The mixture was filtered and the residue taken up in dichloromethane. The dichloromethane was washed with sodium bicarbonate solution, sodium metabisulphite solution, water and brine and then dried and evaporated. Flash chromatography afforded the title compound as an off white solid (857 mg) mp 213°-215° (NMR (CDCl3) delta 7.7 (broad), 7.4 (2H)broad, 7.20(2H)m, 7.12(2H)m, 6.69(1H)d.o.d., 2.79 (6H) 2.60(6H)s.

Provenance & Evidence