m-Chloroperbenzoic acid → HCID 15059546, compound

Participants

Reaction Steps

The product of step (b) above (2 g) was dissolved in dichloromethane (50 mls) and cooled to -10° with stirring. 85% m-chloroperbenzoic acid (1.6 g) was added portionwise. The reaction mixture was slowly warmed to room temperature and after 3 hours the reaction was complete. The reaction mixture was washed with aqueous metabisulphite solution, then bicarbonate solution and finally brine, dried over magnesium sulphate and evaporated to dryness in vacuo, then the residue was purified by flash chromatography (SiO2 /ethyl acetate 3:2 CH2Cl2) to afford the sub-title compound as a yellow crystalline solid, mp 157°-159°.

Provenance & Evidence