Methanol → HCID 19866724, compound

Participants

Reaction Steps

The product of step (d) above (0.99 g) was dissolved in dichloromethane (60 ml) and methanol (5 ml) and cooled to -10°. 85% m-Chloroperbenzoic acid (0.56 g) was added and the whole was slowly warmed to room temperature with stirring. After 2 hours the reaction mixture was washed with metabisulphate solution, then bicarbonate solution and finally with brine, dried over magnesium sulphate and evaporated to dryness in vacuo and the residue was purified by flash chromatography (SiO2 /CH2Cl2 2:3 ethyl acetate) to afford the title compound as a white solid, mp 164°.

Provenance & Evidence