Nitric Acid → HCID 14450250, compound

HRID 1199527Notes

Reaction equation

HRID 1199527 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([N:8]2[CH:12]=[N:11][N:10]=[N:9]2)[CH:5]=[CH:6][CH:7]=1.[N+:13]([O-])([OH:15])=[O:14]>>[CH3:1][C:2]1[CH:3]=[C:4]([N:8]2[CH:12]=[N:11][N:10]=[N:9]2)[CH:5]=[CH:6][C:7]=1[N+:13]([O-:15])=[O:14]

Participants

3

Reactant 2

HCID 944Nitric AcidHCID 14450259HCID 14450259, compound

Product 1

HCID 14450250HCID 14450250, compound

Procedure

1-(3-Methylphenyl)tetrazole (11.3 g) was cautiously added at 0° to fuming nitric acid (100 cm3) with stirring and the solution was then warmed on a steam bath for 5 minutes. The cooled solution was poured onto ice (200 g), and the solid material was filtered off, washed with water (100 cm3) and dried. Recrystallisation from ethyl acetate afforded 1-(3-methyl-4-nitrophenyl)tetrazole, m.p. 166°-168° (9.4 g).

Workup

  1. temperaturethe solution was then warmed on a steam bath for 5 minutes
  2. additionThe cooled solution was poured onto ice (200 g)
  3. filtrationthe solid material was filtered off
  4. washwashed with water (100 cm3)
  5. customdried
  6. customRecrystallisation from ethyl acetate

Sources & evidence

ORD record
ord-754486684a4b40b3ba6e276286e1ed0d
Source dataset
uspto-grants-1990_02
Patent number
US04900839

Reaction notes

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