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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1199542Generated: November 1, 2026

N-methyl-2-pyrrolidone → 4-(4-Amino-3-cyano-5-trifluoromethylphenyl)-1,2,4-triazole

https://huagongshe.com/reaction/1199542

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-methyl-2-pyrrolidoneHCID 13387—
Reactant4-(4-Amino-3-bromo-5-trifluoromethylphenyl)-1,2,4-triazoleHCID 19867072—
Product4-(4-Amino-3-cyano-5-trifluoromethylphenyl)-1,2,4-triazoleHCID 19867073—

Reaction Steps

The following compound, m.p. 283°, was similarly prepared to the previous Preparation using 4-(4-amino-3-bromo-5-trifluoromethylphenyl)-1,2,4-triazole, cuprous cyanide and 1-methyl-2-pyrrolidone as the starting materials: ##STR148##

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04900839
Source datasetuspto-grants-1990_02
ORD IDord-526bb1d4dba542babcf7c8138c0a5664
Source noteuspto-grants-1990_02