Ethanol → HCID 14989651, compound

Participants

Reaction Steps

A solution of 5-benzenesulphonamido-2-(3-cyanopropyl)-3-methylpyridine (1.5 g) in ethanol (100 ml) and 15% w/v sodium hydroxide solution (20 ml) was refluxed for 8 hours. The ethanol was removed under reduced pressure and the pH of the remaining aqueous was adjusted to pH 4 when a white solid crystallised. The solid was collected and recrystallised from methanol to give the title compound (0.7 g) as white needles. m.p. 169°-179° C.

Provenance & Evidence