Toluene → HCID 14051174, compound

Participants

Reaction Conditions

Reaction Steps

To 10 ml of toluene were added 1.0 g of 2-(trans-3-aminostyryl)benzothiazole, 0.78 g of ethyl 4-bromobutyrate and 0.4 g of triethylamine, and the mixture was stirred at 100° C. for 20 hours. After cooled to room temperature, the mixture was extracted with toluene, dried over anhydrous magnesium sulfate and then the solvent was evaporated under reduced pressure. The residue was purified through silica gel column chromatography by use of ethyl acetate-n-hexane to obtain 951 mg of the title compound (yield 66%).

Provenance & Evidence