HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → HCID 54706820, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 4-Hydroxy-1-phenyl-1,8-naphthyridin-2(1H)-one | HCID 54686473 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 54706820 | HCID 54706820 | 65.4% |
Reaction Steps
To a suspension of 4-hydroxy-1-phenyl-1,8-naphthyridin-2(1H)-one (1 g) in CH2Cl2 (20 mL) was added, dropwise and with stirring, a solution of bromine (0.7 g) in CH2Cl2 (5 mL). The mixture was stirred at room temperature overnight, after which time the product was filtered off, dried in air and recrystallized from acetonitrile to yield 0.87 g of the product, m.p. 280° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04902693 |
| Source dataset | uspto-grants-1990_02 |
| ORD ID | ord-f1acfd6cae4c4869bbd7ac59c9c7934e |
| Source note | uspto-grants-1990_02 |