2-Ethoxyacetohydrazide → HCID 19865779, compound

HRID 1199778Notes

Reaction equation

HRID 1199778 reaction equation
[CH2:1]([C:3]1[C:8]2[C:9]([C:15]3[CH:20]=[CH:19][C:18]([CH2:21][CH3:22])=[CH:17][C:16]=3[CH2:23][CH3:24])=[N:10][CH2:11][C:12](=S)[NH:13][C:7]=2[CH:6]=[C:5]([CH2:25][CH3:26])[CH:4]=1)[CH3:2].[CH2:27]([O:29][CH2:30][C:31]([NH:33][NH2:34])=O)[CH3:28]>C(O)CCC>[CH2:1]([C:3]1[C:8]2[C:9]([C:15]3[CH:20]=[CH:19][C:18]([CH2:21][CH3:22])=[CH:17][C:16]=3[CH2:23][CH3:24])=[N:10][CH2:11][C:12]3[N:13]([C:31]([CH2:30][O:29][CH2:27][CH3:28])=[N:33][N:34]=3)[C:7]=2[CH:6]=[C:5]([CH2:25][CH3:26])[CH:4]=1)[CH3:2]

Participants

4

Reactant 2

HCID 147502092-EthoxyacetohydrazideHCID 19865826HCID 19865826, compound

Product 1

HCID 19865779HCID 19865779, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

In the manner given in Example 1, a solution of 1,3-dihydro-6,8-diethyl-5-(2,4-diethylphenyl)-2H-1,4-benzodiazepine-2-thione in n-butyl alcohol was heated to reflux with ethoxyacetic acid hydrazide to give 7,9-diethyl-1-(ethoxymethyl)-6-(2,4-diethylphenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine.

Sources & evidence

ORD record
ord-7232154af1f44d568a59f12a3ec8560e
Source dataset
uspto-grants-1990_02
Patent number
US04902794

Reaction notes

Loading…