HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionordiazepam → 1-(methoxymethyl)-6-phenyl-8-chloro-4H-s-triazolo[4,3-a][1,4]benzodiazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionordiazepam | HCID 826706 | — |
| Reactant | 2-Methoxyacetohydrazide | HCID 2759532 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | 1-(methoxymethyl)-6-phenyl-8-chloro-4H-s-triazolo[4,3-a][1,4]benzodiazepine | HCID 12560614 | — |
Reaction Steps
In the manner given in Example 1, a solution of 1,3-dihydro-7-chloro-5-phenyl-2H-1,4-benzodiazepine-2-thione in n-butyl alcohol was heated to reflux with methoxyacetic acid hydrazide to give 8-chloro-1-(methoxymethyl)-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04902794 |
| Source dataset | uspto-grants-1990_02 |
| ORD ID | ord-b31e6319b51a45a0874678b3c3e141af |
| Source note | uspto-grants-1990_02 |