HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexanoic anhydride → 8-chloro-1-(hydroxymethyl)-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine hexanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexanoic anhydride | HCID 74918 | — |
| Reactant | alpha-Hydroxyalprazolam | HCID 162244 | — |
| Solvent | Water | HCID 962 | — |
| Product | 8-chloro-1-(hydroxymethyl)-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine hexanoate | HCID 70359666 | — |
Reaction Steps
In a manner similar to Example 12, a mixture of 8-chloro-1-(hydroxymethyl)-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine and hexanoic anhydride was heated on the water bath to give 8-chloro-1-(hydroxymethyl)-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine hexanoate (ester).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04902794 |
| Source dataset | uspto-grants-1990_02 |
| ORD ID | ord-f55ee58803374c00b0dcb9fb7f8b386f |
| Source note | uspto-grants-1990_02 |