HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 19865874, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 1,3-Dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-one | HCID 88638 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | HCID 19865891 | HCID 19865891 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 19865874 | HCID 19865874 | — |
Reaction Steps
A mixture of 5.7 g of 2-bromoacetyl-6-methoxynaphthalene (20 mmole), 3.95 g of 4-(2-oxo-1-benzimidazolinyl)-piperidine (18 mmole); b 1.7 g of NaHCO3 (20 mmole) and 60 ml of methanol is refluxed with stirring for 5 hours, then 1.4 g of NaBH4 (37 mmole) dissolved in 7 ml of alkaline water is dropped while maintaining the reaction mixture at the boiling temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04902799 |
| Source dataset | uspto-grants-1990_02 |
| ORD ID | ord-dba7c62ec0b14568b90e5ec89e522d21 |
| Source note | uspto-grants-1990_02 |