HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxylamine → HCID 19865869, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxylamine | HCID 787 | — |
| Reactant | 1-Benzylpiperazine | HCID 75994 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 2-Bromo-1-(6-methoxynaphthalen-2-yl)propan-1-one | HCID 12756327 | — |
| Product | HCID 19865869 | HCID 19865869 | 54% |
Reaction Steps
From 2-bromo-1-(6-methoxy-2-naphtyl)-1-propanone and 1-benzylpiperazine, the compound 2-(4-benzyl-1-piperazinyl)-1-(6-methoxy-2-naphtyl)-1-propanone is prepared (MG 14256; m.p. 89°-91° C., which is reduced with NaBH4 to the corresponding amino alcohol as a mixture of the two stereoisomeric forms which are separated by flash chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04902799 |
| Source dataset | uspto-grants-1990_02 |
| ORD ID | ord-552b72f8e98e48bbb943a352d6dc8adc |
| Source note | uspto-grants-1990_02 |