HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 2-Methoxy-4-(methylamino)-5-nitrophenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | N-methyl-6-nitro-1,3-dioxaindan-5-amine | HCID 13742671 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Methoxy-4-(methylamino)-5-nitrophenol | HCID 13742677 | — |
Reaction Steps
A solution of 0.1 mol (19.6 g) of 2-methylamino-4,5-methylenedioxy-1-nitrobenzene, prepared according to Example 3, in 80 ml of a 30% strength solution of sodium methylate in methanol is brought for 15 minutes to the refluxing temperature of the methanol. The reaction medium is diluted with 500 ml of water. After the filtrate has been neutralized with acetic acid, the expected product precipitates.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04904276 |
| Source dataset | uspto-grants-1990_02 |
| ORD ID | ord-fd2a6e379c2741a8adff488735ab62ea |
| Source note | uspto-grants-1990_02 |