Methanimidic acid, N-cyano-, ethyl ester → HCID 19864119, compound

Participants

Reaction Conditions

Reaction Steps

10.0 g of N-cyanoimidoformic acid ethyl ester are added dropwise to 16.7 g of 4-amino-3,3-dimethylisothiochroman in 10 ml of dry ethanol. The exothermic reaction is complete after 2 hours. The mixture is cooled to 0° C., and the precipitate is filtered off and washed with a small amount of ethanol. After drying, 14.3 g of N-cyano-N'-(3,3-dimethylisothiochroman-4-yl)-formamidine are obtained in the form of colourless crystals having a melting point of 164°-166° C.

Provenance & Evidence