Bromine → 1-Bromo-4-[(4-chlorophenyl)sulfanyl]-3,3-dimethylbutan-2-one

HRID 1199898Notes

Reaction equation

HRID 1199898 reaction equation
[Br:1]Br.[Cl:3][C:4]1[CH:9]=[CH:8][C:7]([S:10][CH2:11][C:12]([CH3:17])([CH3:16])[C:13](=[O:15])[CH3:14])=[CH:6][CH:5]=1>>[Br:1][CH2:14][C:13](=[O:15])[C:12]([CH3:17])([CH3:16])[CH2:11][S:10][C:7]1[CH:6]=[CH:5][C:4]([Cl:3])=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 24408BromineHCID 127659734-[(4-Chlorophenyl)sulfanyl]-3,3-dimethylbutan-2-one

Product 1

HCID 127659741-Bromo-4-[(4-chlorophenyl)sulfanyl]-3,3-dimethylbutan-2-oneYield 99%

Procedure

64 g (0.4 mol) of bromine were slowly added to 97 g (0.4 mol) of 1-(4-chlorophenylmercapto)-2,2-dimethylbutan-3-one at room temperature. The reaction mixture was worked up in a manner corresponding to that in Example 1. 127 g (99% of theory) of 1-bromo-4-(4-chlorophenylmercapto)-3,3-dimethyl-butan-2-one were obtained as a viscous oil. ##STR771##

Sources & evidence

ORD record
ord-d7664306ff3045dda425c9da7af739db
Source dataset
uspto-grants-1990_02
Patent number
US04904297

Reaction notes

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