Diethyl Ether → HCID 12326325, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2-ethylaniline (11.7 g) and diethyl ethoxymethylene malonate (25.0 g) were warmed together at 80° C. for one hour. After cooling, the mixture was poured with stirring into a mixture of 150 ml of ether and 75 ml of hexane. After cooling the solution in an ice bath colorless needles precipitated and were collected by filtration. There was obtained 26.7 g (95%) of the title product; tlc, Rf =0.73, silica gel, ethyl acetate:hexane (1:1).

Provenance & Evidence