Benzyl Bromide → HCID 14210911, compound

Participants

Reaction Steps

3.5 g (10 mmol) of ethyl 4-(2-aminophenyl)-2-methyl-5-oxo-1,4,5,7-tetrahydrofuro[3,4-b]pyridine-3-carboxylate hydrochloride and 1.4 ml (11 mmol) of benzyl bromide are dissolved in 50 ml of absolute acetone, 1.4 g of potassium carbonate are added, and the mixture is stirred overnight at room temperature. The mixture is concentrated, water is added, and the product is filtered off under suction and recrystallized from methanol.

Provenance & Evidence