Ethanimidic acid, ethyl ester, hydrochloride (1:1) → HCID 19864530, compound

Participants

Reaction Steps

2-(4-Hydroxybutylamino)phenylamine (3.6 g) and ethyl acetimidate hydrochloride (3.7 g) was dissolved in ethanol (20 ml) and stirred at room temperature for 11/2 hours. The mixture was evaporated under vacuum and the residue partitioned between ethyl acetate (30 ml) and water (20 ml). The organic phase was separated, dried over Na2SO4, filtered and evaporated to give the title compound as a brown oil (2.8 g).

Provenance & Evidence