Thionyl Chloride → HCID 53789143, compound

HRID 1200048Notes

Reaction equation

HRID 1200048 reaction equation
[S:1]1[C:5]([CH:6]=[CH:7][C:8]2[S:12][C:11]([C:13](O)=[O:14])=[CH:10][CH:9]=2)=[CH:4][C:3]2[CH:16]=[CH:17][CH:18]=[CH:19][C:2]1=2.S(Cl)([Cl:22])=O>ClCCl>[S:1]1[C:5]([CH:6]=[CH:7][C:8]2[S:12][C:11]([C:13]([Cl:22])=[O:14])=[CH:10][CH:9]=2)=[CH:4][C:3]2[CH:16]=[CH:17][CH:18]=[CH:19][C:2]1=2

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 53642175HCID 53642175, compound

Product 1

HCID 53789143HCID 53789143, compoundYield 95.4%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a stirred suspension of 5-[2-(benzo[b]thiophen-2yl)ethenyl]thiophene-2-carboxylic acid (9.11 g) and dichloromethane (900 ml) was added thionyl chloride (7.56 g) over 5 mins. The mixture was refluxed overnight. The solvent was removed in vacuo to give 9.25 g of 5-[2-(benzo[b]thiophen-2-yl)ethenyl]thiophene-2-carboxylic acid chloride.

Workup

  1. temperatureThe mixture was refluxed overnight
  2. customThe solvent was removed in vacuo

Sources & evidence

ORD record
ord-06291c4a7cb540a996b2b85618b3f550
Source dataset
uspto-grants-1990_02
Patent number
US04904674

Reaction notes

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