HCID 14650456, compound → HCID 14650449, compound

HRID 1200193Notes

Reaction equation

HRID 1200193 reaction equation
[C:1]1([C:7]2[O:8][C:9]3[C:17]([CH2:18][C:19]([O:21]CC)=[O:20])=[CH:16][CH:15]=[CH:14][C:10]=3[C:11](=[O:13])[CH:12]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH:2]=1>C(O)(=O)C.O>[C:1]1([C:7]2[O:8][C:9]3[C:17]([CH2:18][C:19]([OH:21])=[O:20])=[CH:16][CH:15]=[CH:14][C:10]=3[C:11](=[O:13])[CH:12]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH:2]=1

Participants

4

Reactant 1

HCID 14650456HCID 14650456, compound

Product 1

HCID 14650449HCID 14650449, compoundYield 68%

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 962WaterSolvent

Procedure

Ethyl [2-(1-cyclohexenyl)-4-oxo-4H-[1]-benzopyran-8-yl]acetate (2.5 g) was dissolved in acetic acid (35 ml) and to the solution was added 50% sulfulic acid (30 ml). The mixture was relfuxed for 4 hours. The reaction mixture was diluted with water and crystals deposited were filtered off and recrystallized from the mixed solvent of ethyl acetate and methanol to obtain the title compound, yield 68%.

Workup

  1. filtrationdeposited were filtered off
  2. customrecrystallized from the mixed solvent of ethyl acetate and methanol

Sources & evidence

ORD record
ord-86bfc59aafc7461d8d9bfb6f89c8fc53
Source dataset
uspto-grants-1990_02
Patent number
US04904690

Reaction notes

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