HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 14302387, compound → HCID 14548113, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 14302387 | HCID 14302387 | — |
| Catalyst | Iron | HCID 23925 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 14548113 | HCID 14548113 | 100.7% |
Reaction Steps
To a suspension of 3-[(1-methyl-2-benzimidazolyl)methoxy]nitrobenzene (8 g) in ethanolic hydrochloric acid is added powdered iron. The reaction is stirred overnight at room temperature. After neutralization with saturated aqueous sodium bicarbonate, the mixture is extracted three times with methylene chloride. The extract is dried over magnesium sulfate and concentrated to give 7.2 g (100% yield) of product, m.p. 149°-153° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04904786 |
| Source dataset | uspto-grants-1990_02 |
| ORD ID | ord-36d47e73fcad4bf5b89461e48d62ab7f |
| Source note | uspto-grants-1990_02 |