Triethylamine → HCID 19864849, compound

Participants

Reaction Steps

To a solution of 3-[(1-methyl-2-benzimidazolyl)methoxy]benzenamine (2 g) and triethylamine (0.79 g) in tetrahydrofuran (100 ml) at room temperature is slowly added a solution of ethanesulfonyl chloride (1.0 g) in tetrahydrofuran. The reaction is stirred for 1 hour. The mixture is filtered through a pad of Celite and silica gel and the solvent is removed in vacuo giving an oil. The oil is purified by HPLC and crystallized from hexane to give 1.0 g (37% yield) of product, m.p. 169°-173° C.

Provenance & Evidence