1-methyl-2-(piperazin-1-yl)-1H-benzo[d]imidazole → 9-{4-[4-(1-methyl-benzimidazol-2-yl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic acid-(2,2,2-trifluoro-ethyl)-amide

HRID 1200450Notes

Reaction equation

HRID 1200450 reaction equation
[CH3:27][n:28]1[c:29]([N:37]2[CH2:38][CH2:39][NH:40][CH2:41][CH2:42]2)[n:30][c:31]2[c:32]1[cH:33][cH:34][cH:35][cH:36]2.[F:1][C:2]([CH2:3][NH:4][C:5](=[O:6])[C:7]1([CH2:20][CH2:21][CH2:22][CH2:23][Br:24])[c:8]2[cH:9][cH:10][cH:11][cH:12][c:13]2-[c:14]2[cH:15][cH:16][cH:17][cH:18][c:19]21)([F:25])[F:26]>>[F:1][C:2]([CH2:3][NH:4][C:5](=[O:6])[C:7]1([CH2:20][CH2:21][CH2:22][CH2:23][N:40]2[CH2:39][CH2:38][N:37]([c:29]3[n:28]([CH3:27])[c:32]4[c:31]([n:30]3)[cH:36][cH:35][cH:34][cH:33]4)[CH2:42][CH2:41]2)[c:8]2[cH:9][cH:10][cH:11][cH:12][c:13]2-[c:14]2[cH:15][cH:16][cH:17][cH:18][c:19]21)([F:25])[F:26]

Participants

3

Reactant 2

HCID 6675511-methyl-2-(piperazin-1-yl)-1H-benzo[d]imidazoleHCID 105264379-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide

Product 1

HCID 226362419-{4-[4-(1-methyl-benzimidazol-2-yl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic acid-(2,2,2-trifluoro-ethyl)-amide

Sources & evidence

ORD record
ord-5f118950fad54e59af9ac697d7a9a080
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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