1-(3-Fluorobenzyl)-1H-indazol-5-amine → tert-Butyl 3-cyano-4-{[1-(3-fluorobenzyl)-1H-indazol-5-yl]amino}-5,8-dihydrothieno[2,3-b:5,4-c']-dipyridine-7(6H)-carboxylate

HRID 1200665Notes

Reaction equation

HRID 1200665 reaction equation
[Cl:19][c:20]1[c:21]2[c:22]([n:23][cH:24][c:25]1[C:26]#[N:27])[s:28][c:29]1[c:34]2[CH2:33][CH2:32][N:31]([C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])[CH2:30]1.[F:1][c:2]1[cH:3][c:4]([CH2:5][n:6]2[n:7][cH:8][c:9]3[cH:10][c:11]([NH2:15])[cH:12][cH:13][c:14]23)[cH:16][cH:17][cH:18]1>>[F:1][c:2]1[cH:3][c:4]([CH2:5][n:6]2[n:7][cH:8][c:9]3[cH:10][c:11]([NH:15][c:20]4[c:21]5[c:22]([n:23][cH:24][c:25]4[C:26]#[N:27])[s:28][c:29]4[c:34]5[CH2:33][CH2:32][N:31]([C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])[CH2:30]4)[cH:12][cH:13][c:14]23)[cH:16][cH:17][cH:18]1

Participants

3

Reactant 2

HCID 71470731-(3-Fluorobenzyl)-1H-indazol-5-amineHCID 58116935tert-Butyl 4-chloro-3-cyano-5,8-dihydrothieno[2,3-b:5,4-c']dipyridine-7(6H)-carboxylate

Product 1

HCID 58116903tert-Butyl 3-cyano-4-{[1-(3-fluorobenzyl)-1H-indazol-5-yl]amino}-5,8-dihydrothieno[2,3-b:5,4-c']-dipyridine-7(6H)-carboxylate

Sources & evidence

ORD record
ord-d9e35f06c9ed483daddb0c62dbcd5f37
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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