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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1200786Generated: October 25, 2026

Toluene → tert-butyl N-[5-[4-(3-methylmorpholin-4-yl)-6-(methylsulfonylmethyl)pyrimidin-2-yl]-1,3-thiazol-2-yl]-N-[(2-methylpropan-2-yl)oxycarbonyl]carbamate

https://huagongshe.com/reaction/1200786

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladiumHCID 23938—
Reactanttert-butyl N-[(2-methylpropan-2-yl)oxycarbonyl]-N-(5-tributylstannyl-1,3-thiazol-2-yl)carbamateHCID 59380135—
Reactant4-[2-Chloro-6-(methylsulfonylmethyl)pyrimidin-4-yl]-3-methylmorpholineHCID 76561900—
Producttert-butyl N-[5-[4-(3-methylmorpholin-4-yl)-6-(methylsulfonylmethyl)pyrimidin-2-yl]-1,3-thiazol-2-yl]-N-[(2-methylpropan-2-yl)oxycarbonyl]carbamateHCID 178431547—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-e765a771c0654292a98283bbba18c066
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)